Click Synthesis of 5-Substituted 1H-Tetrazoles from Aldehydes, Hydroxylamine, and [bmim]N3 via One-Pot, Three-Component Reaction
Majid M. Heravi*, Azadeh Fazeli, Hossein A. Oskooie, Yahya S. Beheshtiha, Hassan Valizadeh
*Department of Chemistry, School of Science, Alzahra University, Vanak, Tehran, Iran, Email: mmh1331yahoo.com
M. M. Heravi, A. Fazeli, H. A. Oskooie, Y. S. Beheshtiha, H. Valizadeh, Synlett, 2012, 23, 2927-2930.
DOI: 10.1055/s-0032-1317671
Abstract
An easy and efficient one-pot, three-component reaction of aldehydes, hydroxylamine, and [bmim]N3 enables the synthesis of 5-substituted 1H-tetrazole derivatives.
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Key Words
5-substituted 1H-tetrazoles, multicomponent reactions, click reaction, cyclization, aldehydes, 1-butyl-3-methylimidazolium azide
ID: J60-Y2012-3730