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Carbazoles via AuCl3-Catalyzed Cyclization of 1-(Indol-2-yl)-3-alkyn-1-ols

Youai Qiu, Wangqing Kong, Chunling Fu and Shengming Ma*

*Laboratory of Molecular Recognition and Synthesis, Department of Chemistry, Zhejiang University, Hangzhou 310027, Zhejiang, P. R. China, Email:

Y. Qiu, W. Kong, C. Fu, S. Ma, Org. Lett., 2012, 14, 6198-6201.

DOI: 10.1021/ol3029498 (free Supporting Information)


AuCl3-catalyzed cyclizations of 1-(indol-2-yl)-3-alkyn-1-ols occurred smoothly in toluene at room temperature leading to a series of carbazole derivatives efficiently. A possible mechanism has been proposed.

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ID: J54-Y2012-3870