Organic Chemistry Portal

Abstracts

Search:

Copper-Catalyzed C-O Bond Formation: An Efficient One-Pot Highly Regioselective Synthesis of Furans from (2-Furyl)Carbene Complexes

Hua Cao*, Haiying Zhan, Jinghe Cen, Jingxin Lin, Yuanguang Lin, Qiuxia Zhu, Minling Fu and Huanfeng Jiang*

*Guangdong Pharmaceutical University, Guangzhou 510006 and South China University of Technology, Guangzhou 510640, P. R. China, Email: caohuagdpu.edu.cn, jianghfscut.edu.cn

H. Cao, H. Zhan, J. Cen, J. Lin, Y. Lin, Q. Zhu, M. Fu, H. Jiang, Org. Lett., 2013, 15, 1080-1083.

DOI: 10.1021/ol400080e (free Supporting Information)



see article for more reactions

Abstract

A convenient one-pot Cu(I)-catalyzed strategy gives trisubstituted α-carbonyl furans derivatives in good yields via (2-furyl) carbene complexes using air as the oxidant.

see article for more examples



Key Words

Furans, Oxygen


ID: J54-Y2013-0550