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A Mild and Highly Efficient Conversion of Arylboronic Acids into Phenols by Oxidation with MCPBA

Dong-Song Chen, Jing-Mei Huang*

*School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, Guangdong 510640, P. R. of China, Email: chehjmscut.edu.cn

D.-S. Chen, J.-M. Huang, Synlett, 2013, 24, 499-501.

DOI: 10.1055/s-0032-1318197 (free Supporting Information)


Abstract

The use of MCPBA achieves a mild and highly efficient synthesis of phenols from arylboronic acids in a aqueous solution at room temperature. Isotopical labeling studies show that the hydroxyl oxygen atom of the phenol might originate from the MCPBA.

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Key Words

arylboronic acids, efficiency, MCPBA, oxidation, phenols


ID: J60-Y2013-0570