Synthesis of 2-Substituted Benzothiazoles from 1-Iodo-2-nitrobenzenes by a Copper-Catalyzed One-Pot Three-Component Reaction
Jidan Liu, Qingwen Gui, Zhiyong Yang, Ze Tan*, Ruqing Guo, Ji-Cheng Shi*
*Hunan University, Changsha 410082 and Guangdong University
of Petrochemical Technology, Maoming, Guangdong 525000, P. R. of China, Email:
ztanze
gmail.com, jchshi_mmc126.com
J. Liu, Q. Gui, Z. Yang, Z. Tan, R. Guo, J.-C. Shi, Synthesis, 2013, 45, 943-951.
DOI: 10.1055/s-0032-1318304
Abstract
A copper-catalyzed, one-pot, three-component reaction of 1-iodo-2-nitroarenes with sodium sulfide and an aldehyde gives 2-substituted 1,3-benzothiazoles in good yields.
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Key Words
catalysis, copper, multicomponent reactions, heterocycles, benzothiazoles, cyclizations, sulfur
ID: J66-Y2013-0920
