Organic Chemistry Portal

Abstracts

Search:

Arylation of Aldehyde Homoenolates with Aryl Bromides

Kevin Cheng and Patrick J. Walsh*

*Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, Pennsylvania 19104-6323, United States, Email: pwalshsas.upenn.edu

K. Cheng, P. J. Walsh, Org. Lett., 2013, 15, 2298-2301.

DOI: 10.1021/ol4008876


Abstract

A mild palladium catalyzed coupling of reactive aldehyde homoenolates, that are generated by ring opening of cyclopropanols, with aryl bromides gives aldehyde products at room temperature in good yield.

see article for more examples



Key Words

Arylation


ID: J54-Y2013