Organic Chemistry Portal

Abstracts

Search:

4-(N,N-Dimethylamino)pyridine Hydrochloride as a Recyclable Catalyst for Acylation of Inert Alcohols: Substrate Scope and Reaction Mechanism

Zhihui Liu, Qiaoqiao Ma, Yuxiu Liu and Qingmin Wang*

*State Key Laboratory of Elemento-Organic Chemistry, Research Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China, Email: wangqmnankai.edu.cn

Z. Liu, Y. Liu, Q. Wang, Org. Lett., 2014, 16, 236-239.

DOI: 10.1021/ol4030875


Abstract

4-(N,N-Dimethylamino)pyridine hydrochloride (DMAP·HCl) was used as a recyclable catalyst for the acylation of inert alcohols and phenols under base-free conditions. The catalyst can be reused more than eight times without loss in activity and works with various acylating reagents.

see article for more examples



Key Words

acylation, acetates, pivalates, benzoates


ID: J54-Y2014