Three-Component Reaction between Alkynes, Elemental Sulfur, and Aliphatic Amines: A General, Straightforward, and Atom Economical Approach to Thioamides
Thanh Binh Nguyen*, Minh Quan Tran, Ludmila Ermolenko and Ali Al-Mourabit
*Centre de Recherche de Gif-sur-Yvette, Institut de Chimie
des Substances Naturelles, CNRS, 91198 Gif-sur-Yvette Cedex, France, Email:
nguyen
icsn.cnrs-gif.fr
T. B. Nguyen, M. Q. Tran, L. Ermolenko, A. Al-Mourabit, Org. Lett., 2014, 16, 310-313.
DOI: 10.1021/ol403345e
Abstract
A three-component reaction of alkynes, elemental sulfur, and aliphatic amines allows a general, straightforward, and atom-economical synthesis of thioamides.
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Key Words
Thiolation, Hydroamination, Multicomponent Reactions
ID: J54-Y2014
