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A Robust, Moisture- and Air-Stable Phosphine Mono-Ylide Palladacycle Precatalyst: A Simple and Highly Efficient System for Mizoroki-Heck Reactions

Seyyed Javad Sabounchei*, Mohsen Ahmadi, Tayebeh Azizi, Mohammad Panahimehr

*Faculty of Chemistry, Bu-Ali Sina University, Hamedan, 65174, Iran, Email: jsabouncheiyahoo.co.uk

S. J. Sabounchi, M. Ahmadi, T. Azizi, M. Panahimehr, Synlett, 2014, 25, 336-342.

DOI: 10.1055/s-0033-1340319 (free Supporting Information)


Abstract

A palladacycle phosphine mono-ylide complex is as an efficient catalyst for the Mizoroki-Heck cross-coupling reaction of aromatic or aliphatic olefins with a broad range of aryl bromides and chlorides. The reactions proceeded in good yields in the presence of low loadings of palladium (10 ppm) under aerobic conditions. High catalyst activities with turnover frequencies of up to 20,000 h-1 were observed at 130C.

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Key Words

olefination, catalysis, palladium, ylides, Heck reaction


ID: J60-Y2014