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Copper-Catalyzed N-Arylation of Sulfonamides with Boronic Acids in Water under Ligand-Free and Aerobic Conditions

Mahmoud Nasrollahzadeh*, Ali Ehsani, Mehdi Maham

*Department of Chemistry, Faculty of Science, University of Qom, PO Box 3716146611, Qom, Iran, Email: mahmoudnasr81gmail.com

M. Nasrollahzadeh, A. Ehsani, M. Maham, Synlett, 2014, 25, 505-508.

DOI: 10.1055/s-0033-1340475 (free Supporting Information)


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Abstract

An efficient method for the copper-catalyzed arylation of sulfonamides in water under ligand-free conditions offers high yields, simple workup procedure, and elimination of toxic materials.


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Key Words

Chan-Lam coupling, arylation, ligand-free, copper, boronic acids, sulfonamides, water, green chemistry


ID: J60-Y2014