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Synthesis of Isatins by I2/TBHP Mediated Oxidation of Indoles

You Zi, Zhong-Jian Cai, Shun-Yi Wang* and Shun-Jun Ji*

*Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Soochow University, Suzhou 215123, China, Email: shunyisuda.edu.cn, shunjunsuda.edu.cn

Y. Zi, Z.-J. Cai, S.-Y. Wang, S.-J. Ji, Org. Lett., 2014, 16, 3094-3097.

DOI: 10.1021/ol501203q (free Supporting Information)


Abstract

An I2/TBHP-mediated oxidation of commercially available indoles affords isatins in moderate to good yields.

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Key Words

isatins, iodine, TBHP


ID: J54-Y2014