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Selective Aerobic Oxidation of Alcohols to Aldehydes, Carboxylic Acids, and Imines Catalyzed by a Ag-NHC Complex

Lei Han, Ping Xing and Biao Jiang*

*CAS Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032, China, Email: jiangbsioc.ac.cn

L. Han, P. Xing, B. Jiang, Org. Lett., 2014, 16, 3428-3431.

DOI: 10.1021/ol501353q (free Supporting Information)


Abstract

The use of low loadings of a silver NHC catalysts enables a mild, selective oxidation of alcohols to aldehydes or carboxylic acids in the presence of BnMe3NOH or KOH under dry air in excellent yield. The catalytic system can also be used for a one-pot synthesis of imines in excellent yield.

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Key Words

aldehydes, carboxylic acids, imines, air


ID: J54-Y2014