Synthesis of 3-Pyrrolin-2-ones by Rhodium-Catalyzed Transannulation of 1-Sulfonyl-1,2,3-triazole with Ketene Silyl Acetal
Rui-Qiao Ran, Jun He, Shi-Dong Xiu, Kai-Bing Wang and Chuan-Ying Li*
*Department of Chemistry, Zhejiang Sci-Tech University,
Xiasha West Higher Education District, Hangzhou 310018, China, Email: licy
zstu.edu.cn
R.-Q. Ran, J. He, S.-D. Xiu, K.-B. Wang, C.-Y. Li, Org. Lett., 2014, 16, 3704-3705.
DOI: 10.1021/ol501514b
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Abstract
A 3 + 2 cycloaddition of α-imino rhodium carbenoids generated from 1-sulfonyl 1,2,3-triazoles with ketene silyl acetals offers a novel and straightforward synthesis of biologically interesting 3-pyrrolin-2-ones with broad substrate scope.
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Key Words
ID: J54-Y2014
