Fe-Catalyzed Direct Dithioacetalization of Aldehydes with 2-Chloro-1,3-dithiane
Junshan Lai, Wenbin Du, Lixia Tian, Changgui Zhao, Xuegong She and Shouchu Tang*
*School of Pharmacy, Lanzhou University, Lanzhou 730000, P. R. China, Email: tangshchlzu.edu.cn
J. Lai, W. Du, L. Tian, C. Zhou, X. She, S. Tang, Org. Lett., 2014, 16, 4396-4399.
DOI: 10.1021/ol502276r (free Supporting Information)
A catalytic dithioacetalization of aldehydes in the presence of iron catalyst provides access to 1,3-dithianes using 2-chloro-1,3-dithiane under mild conditions. This highly efficient dithioacetaliation process results in good to excellent yields.
see article for more examples