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Clay-Supported Copper Nitrate (Claycop): A Mild Reagent for the Selective Nitration of Aromatic Olefins

Eeshwaraiah Begari*, Chandani Singh, U. Nookaraju, Pradeep Kumar

*Division of Organic Chemistry, CSIR-National Chemical Laboratory, Pune 411008, India, Email: e.begarincl.res.in

E. Begari, C. Singh, U. Nookaraju, P. Kumar, Synlett, 2014, 25, 1997-2000.

DOI: 10.1055/s-0034-1378513 (free Supporting Information)


Abstract

A clay-supported copper nitrate (Claycop) and a catalytic amount of (2,2,6,6-tetramethylpiperidin-1-yl)oxyl enable an inexpensive and mild reagent system for the nitration of a wide variety of aromatic and aliphatic olefins. High conversions and exclusive E-selectivity, together with the environmentally benign nature of the Claycop reagent, make this a green method and an attractive alternative to established methods.

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Key Words

nitrations, alkenes, oxygen


ID: J60-Y2014