Unprecedented Catalytic Activity of Fe(NO3)3·9H2O: Regioselective Synthesis of 2-Nitroimidazopyridines via Oxidative Amination
Kamarul Monir, Avik Kumar Bagdi, Monoranjan Ghosh and Alakananda Hajra*
*Department of Chemistry, Visva-Bharati (A Central
University), Santiniketan 731235, India, Email: alakananda.hajra
visva-bharati.ac.in
K. Monir, A. K. Bagdi, M. Ghosh, A. Hajra, Org. Lett., 2014, 16, 4630-4633.
DOI: 10.1021/ol502218u
Abstract
An oxidative diamination of nitroalkene with 2-aminopyridine for the synthesis of 2-nitro-3-arylimidazo[1,2-a]pyridines with complete regioselectivity has been achieved under mild and aerobic reaction conditions using an iron catalyst. 2-nitroimidazo[1,2-a]pyridines can also be synthesized directly from styrenes.
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Key Words
ID: J54-Y2014
