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Lithium(1+)-Catalyzed Nazarov-Type Cyclization of 1-Arylbuta-2,3-dien-1-ols: Synthesis of Benzofulvene Derivatives

Masahiro Sai, Seijiro Matsubara*

*Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto-daigaku Katsura, Nishikyo-ku, Kyoto 615-8510, Japan, Email: matsubara.seijiro.2ekyoto-u.ac.jp

M. Sai, S. Matubara, Synlett, 2014, 25, 2067-2071.

DOI: 10.1055/s-0034-1378333 (free Supporting Information)


Abstract

Lithium hexafluorophosphate is an effecient catalyst for a Nazarov-type cyclization of 1-arylbuta-2,3-dien-1-ols into benzofulvenes, which are valuable building blocks for functional materials and bioactive compounds.


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Key Words

catalysis, cyclizations, benzofulvenes, indenes, dienols, lithium, Nazarov reaction


ID: J60-Y2014