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Facile Synthesis of γ-Ketophosphonates by an Intermolecular Stetter Reaction onto Vinylphosphonates

Atanu Patra, Anup Bhunia and Akkattu T. Biju*

*Organic Chemistry Division, CSIR-National Chemical Laboratory (CSIR-NCL), Dr. Homi Bhabha Road, Pune 411008, India, Email: atbijuiisc.ac.in

A. Patra, A. Bhunia, A. T. Biju, Org. Lett., 2014, 16, 4798-4801.

DOI: 10.1021/ol502262d (free Supporting Information)


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Abstract

The N-heterocyclic carbene derived from N-mesitylimidazolium chloride was an effective catalyst for a Stetter reaction of aromatic aldehydes with vinylphosphonates providing γ-ketophosphonates in good yields.

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Key Words

Stetter Reaction, Phosphonates


ID: J54-Y2014