Transition-Metal-Catalyzed Synthesis of 1,3-Diynes and Ynamides from 2-Bromo-1-iodoalkenes
Jun Xue, Miao-Ting Luo, Yue-Lu Wen, Min Ye, Liang-Xian Liu, Zheng-Wang Chen*
*Key Laboratory of Organo-Pharmaceutical Chemistry of Jiangxi
Province, Gannan Normal University, Ganzhou 341000, P. R. of China, Email:
chenzwang
gnnu.cn
J. Xue, M.-T. Luo, Y.-L. Wen, M. Ye, L.-X. Liu, Z.-W. Chen, Synthesis, 2014, 46, 3191-3198.
DOI: 10.1055/s-0034-1378652
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Abstract
An efficient palladium-catalyzed homocoupling reaction of 2-bromo-1-iodoalkenes gives 1,3-diynes. Moreover, ynamides can be synthesized in high yields from 2-bromo-1-iodoalkenes and carbamates using nanoparticulate copper(I) oxide as catalyst.
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Key Words
catalysis, palladium, copper, alkynes, amides, carbamates, coupling
ID: J66-Y2014
