Single-Electron Transmetalation: An Enabling Technology for Secondary Alkylboron Cross-Coupling
David N. Primer, Idris Karakaya, John C. Tellis and Gary A. Molander*
*Roy and Diana Vagelos Laboratories, Department of Chemistry,
University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, United States, Email:
gmolandr
sas.upenn.edu
D. N. Primer, I. Karakaya, J. C. Tellis, G. A. Molander, J. Am. Chem. Soc., 2015, 137, 2195-2198.
DOI: 10.1021/ja512946e
Abstract
Single-electron-mediated alkyl transfer enables a cross-coupling of secondary alkyltrifluoroborates with an array of aryl bromides under mild conditions. The reaction is mediated by an Ir photoredox catalyst and a Ni cross-coupling catalyst.
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Key Words
ID: J48-Y2015
