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Ligand-Free, Palladium-Catalyzed Dihydrogen Generation from TMDS: Dehalogenation of Aryl Halides on Water

Anish Bhattacharjya, Piyatida Klumphu and Bruce H. Lipshutz*

*Department of Chemistry & Biochemistry, University of California, Santa Barbara, California 93106, United States, Email: lipshutzchem.ucsb.edu

A. Bhattacharjya, P. Klumphu, B. H. Lipshutz, Org. Lett., 2015, 17, 1122-1125.

DOI: 10.1021/ol5037369 (free Supporting Information)


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Abstract

Nanoparticles formed from PdCl2 in the presence of tetramethyldisiloxane (TMDS) on water enable a mild and environmentally attractive dehalogenation of functionalized aryl halides. The reaction medium with the catalyst can be recycled.


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Key Words

Dehalogenations, TMDS, Green Chemistry


ID: J54-Y2015