Catalytic Trifluoromethylation of Aryl- and Vinylboronic Acids by 2-Cyclopropyl-1-(trifluoromethyl)benzo[b]thiophenium Triflate
Sadayuki Arimori and Norio Shibata*
*Department of Frontier Materials, Nagoya Institute of
Technology, Gokiso, Showa-ku, Nagoya 466-8555, Japan, Email: nozshiba
nitech.ac.jp
S. Arimori, N. Shibata, Org. Lett., 2015, 17, 1632-1635.
DOI: 10.1021/acs.orglett.5b00164
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Abstract
Catalytic trifluoromethylation of aryl- and vinylboronic acids by 2-cyclopropyl-1-(trifluoromethyl)benzo[b]thiophenium proceeded in good yields for various substrates in the presence of a catalytic amount of CuOAc and 2,4,6-collidine in ethyl acetate under mild reaction conditions at room temperature.
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Key Words
ID: J54-Y2015
