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Green and Efficient: Iron-Catalyzed Selective Oxidation of Olefins to Carbonyls with O2

Angela Gonzalez-de-Castro and Jianliang Xiao*

*Department of Chemistry, University of Liverpool, Liverpool L69 7ZD, U.K., Email: jxiaoliv.ac.uk

A. Gonzalez-de-Castro, J. Xiao, J. Am. Chem. Soc., 2015, 137, 8206-8218.

DOI: 10.1021/jacs.5b03956 (free Supporting Information)



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Abstract

A mild and operationally simple protocol for the selective aerobic oxidation of aromatic olefins to carbonyl compounds is catalyzed by a Fe(III) species bearing a pyridine bisimidazoline ligand at 1 atm of O2. The method cleaves α- and β-substituted styrenes to afford benzaldehydes and aromatic ketones in high yields with excellent chemoselectivity and very good functional group tolerance.

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Key Words

ketones, aldehydes, oxygen


ID: J48-Y2015