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Ni-Catalyzed Regioselective Hydrocarboxylation of Alkynes with CO2 by Using Simple Alcohols as Proton Sources

Xueqiang Wang, Masaki Nakajima and Ruben Martin*

*Institute of Chemical Research of Catalonia (ICIQ), Av. Pa´sos Catalans 16, 43007 Tarragona, Spain, Email: rmartinromoiciq.es

X. Wang, M. Nakajima, R. Martin, J. Am. Chem. Soc., 2015, 137, 8924-8927.

DOI: 10.1021/jacs.5b05513 (free Supporting Information)


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Abstract

A mild and user-friendly Ni-catalyzed regioselective hydrocarboxylation enables a regioselective conversion of a broad range of alkynes with CO2 (1 bar) while obviating the need for sensitive organometallic species and using simple alcohols as proton sources.

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Key Words

α,β-unsaturated compounds, manganese


ID: J48-Y2015