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Pd(0)-Catalyzed Cross-Coupling of 1,1-Diboronates with 2,2′-Dibromobiphenyls: Synthesis of 9H-Fluorenes

Shuai Xu, Xianghang Shangguan, Huan Li*, Yan Zhang and Jianbo Wang*

*Beijing National Laboratory of Molecular Sciences (BNLMS), College of Chemistry, Peking University, Beijing 100871, China, Email: lihuan8761163.com, wangjbpku.edu.cn

S. Xu, X. Shangguan, H. Li, Y. Zhang, J. Wang, J. Org. Chem., 2015, 80, 7779-7784.

DOI: 10.1021/acs.joc.5b01100


Abstract

An efficient synthesis of 9H-fluorene derivatives through a Pd(0)-catalyzed cross-coupling reaction of 1,1-diboronates with 2,2′-dibromobiphenyls offers high yields, operational simplicity, and mild reaction conditions.

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Key Words

9H-fluorenes, alkylation, Suzuki Coupling


ID: J42-Y2015