Organic Chemistry Portal

Abstracts

Search:

Copper N-Heterocyclic Carbene: A Catalyst for Aerobic Oxidation or Reduction Reactions

Le-Wu Zhan, Lei Han, Ping Xing and Biao Jiang*

*School of Chemical Engineering, Nanjing University of Science and Technology, 200 Xiaolingwei, Nanjing 210094, China, Email: jiangbmail.sioc.ac.cn

L.-W. Zhan, L. Han, P. Xing, B. Jiang, Org. Lett., 2015, 17, 5990-5993.

DOI: 10.1021/acs.orglett.5b02756 (free Supporting Information)


see article for more reactions

Abstract

Copper N-heterocyclic carbene complexes serve as catalysts for both aerobic oxidation of alcohols to aldehydes and reduction of imines to amines. A one-pot tandem synthetic strategy affords useful secondary amines from benzylic alcohols and anilines via an oxidation-reduction strategy.

see article for more examples



Key Words

aldehydes, reductive amination, aryl amines, oxygen, PMHS


ID: J54-Y2015