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Direct Synthesis of N-Unsubstituted 4-Aryl-1,2,3-triazoles Mediated by Amberlyst-15

Hui Zhang, Dao-Qing Dong, Zu-Li Wang*

*College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Qingdao, 266109, P. R. of China, Email: wangzulichem163.com

H. Zhang, D.-Z. Dong, Z.-L. Wang, Synthesis, 2016, 48, 131-135.

DOI: 10.1055/s-0035-1560488 (free Supporting Information)


Abstract

A highly efficient and effective synthesis of N-unsubstituted 4-aryl-1,2,3-triazoles is promoted by Amberlyst-15. The ion exchange resin can be recycled and reused up to eight times without loss of catalytic activity.

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Key Words

1,2,3-triazoles, Amberlyst-15, 1,3-dipolar cycloadditions


ID: J66-Y2016