Transition Metal-Free Visible Light-Driven Photoredox Oxidative Annulation of Arylamidines
Zi-chao Shen, Pan Yang and Yu Tang*
*School of Pharmaceutical Science and Technology, Key Laboratory for Modern Drug Delivery & High-Efficiency, Tianjin University, Tianjin, 300072 P. R. China, Email: yutangtju.edu.cn
Z.-c. Shen, P. Yang, Y. Tang, J. Org. Chem., 2016, 81, 309-317.
DOI: 10.1021/acs.joc.5b02366
Abstract
A metal-free visible light-mediated oxidative coupling catalyzed by a photoredox organocatalyst enables a fast synthesis of multisubstituted quinazolines from readily available amidines. The protocol features low catalyst loading.
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ID: J42-Y2016