Organic Chemistry Portal

Abstracts

Search:

Phosphorous Acid Promoted Hydration-Condensation of Aromatic Alkynes with Aldehydes Affording Chalcones in an Oil/Water Two-Phase System

Yongbo Zhou*, Zhongwen Li, Xiao Yang, Xiulin Chen, Mei Li, Tieqiao Chen, Shuang-Feng Yin*

*State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. of China, Email: sf_yinhnu.edu.cn

Y. Zhou, Z. Li, X. Yang, X. Chen, M. Li, T. Chen, S.-F. Yin, Synthesis, 2016, 48, 231-237.

DOI: 10.1055/s-0035-1560832 (free Supporting Information)


Abstract

A phosphorous acid promoted alkyne-aldehyde hydration-condensation enables a simple and environmentally benign synthesis of chalcones in high to excellent yields in an oil/water two-phase system.

see article for more examples



Key Words

phosphorous acids, two-phase systems, chalcones, hydration, condensation, green chemistry


ID: J66-Y2016