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m-CPBA Mediated Metal Free, Rapid Oxidation of Aliphatic Amines to Oximes

Vilas V. Patil, Eknath M. Gayakwad and Ganapati S. Shankarling*

*Department of Dyestuff Technology, Institute of Chemical Technology, N. P. Marg, Matunga, Mumbai 400019, India, Email: gs.shankarlingictmumbai.edu.in

V. V. Patil, E. M. Gayakwad, G. S. Shankarling, J. Org. Chem., 2016, 81, 781-786.

DOI: 10.1021/acs.joc.5b01740 (free Supporting Information)


Abstract

The use of m-CPBA as an oxidant in ethyl acetate enables an efficient, rapid oxidation of various aliphatic amines to oximes in high conversion with >90% oxime selectivity at room temperature under catalyst-free conditions.


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Key Words

oximes (oxidation, hydroxylation), MCPBA


ID: J42-Y2016