Organic Chemistry Portal

Abstracts

Search:

Copper-Catalyzed Hydroamination of Terminal Allenes

Rémi Blieck, Janet Bahri, Marc Taillefer* and Florian Monnier*

*Ecole Nationale Supérieure de Chimie De Montpellier, AM2N, 8 rue de l’Ecole Normale, Montpellier 34296 Cedex 5, France, Email: marc.tailleferenscm.fr, florian.monnierenscm.fr

R. Blieck, J. Bahri, M. Taillefer, F. Monnier, Org. Lett., 2016, 18, 1482-1485.

DOI: 10.1021/acs.orglett.6b00452 (free Supporting Information)



see article for more reactions

Abstract

A ligand-free copper-catalyzed hydroamination of allenes with cyclic secondary amines or anilines derivatives provides (E)-allylamines under smooth conditions with total regio- and stereoselectivity.


see article for more examples



Key Words

allylic amines, arylamines


ID: J54-Y2016