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Nickel-Catalyzed Phosphorylation of Phenol Derivatives via C-O/P-H Cross-Coupling

Jia Yang, Jing Xiao, Tieqiao Chen* and Li-Biao Han*

*College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China; AIST, Tsukuba, Ibaraki 305-8565, Japan, Email: chentieqiaohnu.edu.cn, libiao-hanaist.go.jp

J. Yang, J. Xiao, T. Chen, L.-B. Han, J. Org. Chem., 2016, 81, 3911-3916.

DOI: 10.1021/acs.joc.6b00289 (free Supporting Information)


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Abstract

In an efficient nickel-catalyzed phosphorylation, various phenyl pivalates coupled readily with hydrogen phosphoryl compounds to afford the corresponding aryl phosphonates and aryl phosphine oxides in very good yields.

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plausible mechanism



Key Words

phosphonates


ID: J42-Y2016