Palladium-Catalyzed Synthesis of Alkynes via a Tandem Decarboxylation/Elimination of (E)-Enol Triflates
Charissa Munteanu and Doug E. Frantz*
*Department of Chemistry, The University of Texas at San Antonio, One UTSA Circle, San Antonio, Texas 78249, United States, Email: doug.frantzutsa.edu
C. Munteanu, D. E. Frantz, Org. Lett., 2016, 18, 3937-3939.
DOI: 10.1021/acs.orglett.6b01904
Abstract
A mild catalytic synthesis of alkynes via a tandem Pd-catalyzed decarboxylation/elimination of enol triflates as readily available starting materials. The method offers broad functional group tolerance, and the ability to access terminal, internal, and halogenated alkynes.
see article for more examples
Key Words
ID: J54-Y2016