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Palladium-Catalyzed Synthesis of Alkynes via a Tandem Decarboxylation/Elimination of (E)-Enol Triflates

Charissa Munteanu and Doug E. Frantz*

*Department of Chemistry, The University of Texas at San Antonio, One UTSA Circle, San Antonio, Texas 78249, United States, Email: doug.frantzutsa.edu

C. Munteanu, D. E. Frantz, Org. Lett., 2016, 18, 3937-3939.

DOI: 10.1021/acs.orglett.6b01904


Abstract

A mild catalytic synthesis of alkynes via a tandem Pd-catalyzed decarboxylation/elimination of enol triflates as readily available starting materials. The method offers broad functional group tolerance, and the ability to access terminal, internal, and halogenated alkynes.

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Key Words

alkynes


ID: J54-Y2016