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Photocatalytic Decarboxylative Hydroxylation of Carboxylic Acids Driven by Visible Light and Using Molecular Oxygen

Hai-Tao Song, Wei Ding, Quan-Quan Zhou, Jing Liu, Liang-Qiu Lu* and Wen-Jing Xiao

*Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan, Hubei 430079, China, Email:

H.-T. Song, W. Ding, Q.-Q. Zhou, J. Liu, L.-Q. Lu, W.-J. Xiao, J. Org. Chem., 2016, 81, 7250-7255.

DOI: 10.1021/acs.joc.6b01360 (free Supporting Information)

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A photocatalytic direct decarboxylative hydroxylation of carboxylic acids enables the conversion of various readily available carboxylic acids to alcohols in good yields under extremely mild reaction conditions using molecular oxygen as a green oxidant and visible light as a driving force.

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Key Words

decarboxylation, benzylic alcohols, oxygen, sodium borohydride, organocatalysis, photochemistry

ID: J42-Y2016