Organic Chemistry Portal

Abstracts

Search:

An Indefinitely Air-Stable σ-NiII Precatalyst for Quantitative Cross-Coupling of Unreactive Aryl Halides and Mesylates with Aryl Neopentylglycolboronates

Jagadeesh Malineni, Ryan L. Jezorek, Na Zhang, Virgil Percec*

*Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104-6323, USA, Email: percecsas.upenn.edu

J. Malineni, R. L. Jezorek, N. Zhang, V. Percec, Synthesis, 2016, 48, 2795-2807.

DOI: 10.1055/s-0035-1562342 (free Supporting Information)


see article for more reactions

Abstract

A universal, bench-stable and easily prepared NiIICl(1-naphthyl)(PCy3)2/PCy3 σ-complex enables efficient and quantitative cross-coupling of aryl chlorides, bromides, iodides, mesylates, and fluorides with aryl neopentylglycolboronates.

see article for more examples



Key Words

nickel, Suzuki coupling, quantitative, aryl chlorides, aryl bromides, aryl fluorides, aryl mesylates, biaryls


ID: J66-Y2016