Copper Catalysis for Selective Heterocoupling of Terminal Alkynes
Lebin Su, Jianyu Dong, Long Liu, Mengli Sun, Renhua Qiu, Yongbo Zhou* and Shuang-Feng Yin*
*State Key Laboratory of Chemo/Biosensing and Chemometrics,
College of Chemistry and Chemical Engineering, Hunan University, Changsha
410082, China, Email: zhouyb
hnu.edu.cn, sf_yinhnu.edu.cn
L. Su, J. Dong, L. Liu, M. Sun, R. Qiu, Y. Zhou, S.-F. Yin, J. Am. Chem. Soc., 2016, 138, 12348-12351.
DOI: 10.1021/jacs.6b07984
see article for more reactions
Abstract
A Cu-catalyzed aerobic Glaser-Hay reaction enables a selective heterocoupling of terminal alkynes to provide a broad range of unsymmetrical 1,3-diynes in good to excellent yields.
see article for more examples
Key Words
ID: J48-Y2016
