Organic Chemistry Portal

Abstracts

Search:

Regioselective Iodine-Catalyzed Construction of Polysubstituted Pyrroles from Allenes and Enamines

Yu Wang, Chen-Min Jiang, Hong-Liang Li, Fu-Sheng He, Xiaoyan Luo* and Wei-Ping Deng*

*School of Pharmacy and Shanghai Key Laboratory of New Drug Design, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China, Email: xyluoecust.edu.cn, weiping_dengecust.edu.cn

Y. Wang, C.-M. Jiang, H.-L. Li, F.-S. He, X. Luo, W.-P. Deng, J. Org. Chem., 2016, 81, 8653-8658.

DOI: 10.1021/acs.joc.6b01737



see article for more reactions

Abstract

A iodine-catalyzed tandem Michael addition/oxidative annulation of allenes and enamines provides polysubstituted pyrroles in an efficient and highly regioselective way in good yields under mild conditions.

see article for more examples



Key Words

Pyrroles, TBHP


ID: J42-Y2016