Organic Chemistry Portal



An Efficient and Practical Method for Olefin Dihydroxylation

Zhi-bin Luo*, Chen Zhao, Jimin Xie*, Hong-fei Lu*

*Jiangsu University, Zhenjiang, 212013; Jiangsu University of Science and Technology, Zhenjiang, 212003, P. R. of China, Email:,

Z.-b. Luo, C. Zhao, J. Xie, H.-f. Lu, Synthesis, 2016, 48, 3696-3700.

DOI: 10.1055/s-0035-1562783 (free Supporting Information)

see article for more reactions


An efficient and economic procedure for the dihydroxylation of various olefin derivatives with commercial KMnO4 as the oxidant in the presence of a quaternary ammonium salt is suitable for large-scale production of cis-dihydroxy compounds, even those bearing primary and secondary alcohol groups, without overoxidation.

see article for more examples

Key Words

dihydroxylation, diols, acrylates, alkenes, potassium permanganate, quaternary ammonium salts

ID: J66-Y2016