Active and Recyclable Catalytic Synthesis of Indoles by Reductive Cyclization of 2-(2-Nitroaryl)acetonitriles in the Presence of Co-Rh Heterobimetallic Nanoparticles with Atmospheric Hydrogen under Mild Conditions
Isaac Choi, Hyunho Chung, Jang Won Park and Young Keun Chung*
*Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul 08826, Korea, Email: ykchungsnu.ac.kr
I. Choi, H. Chung, J. W. Park, Y. K. Chung, Org. Lett., 2016, 18, 5456-5459.
DOI: 10.1021/acs.orglett.6b02659 (free Supporting Information)
A cobalt-rhodium heterobimetallic nanoparticle-catalyzed reductive cyclization of 2-(2-nitroaryl)acetonitriles to indoles proceeds without any additives under mild conditions. The catalytic can be reused more than ten times without loss of catalytic activity.
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