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AlkylFluor: Deoxyfluorination of Alcohols

Nathaniel W. Goldberg, Xiao Shen, Jiakun Li and Tobias Ritter*

*Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, D-45470 Mülheim an der Ruhr, Germany, Email: rittermpi-muelheim.mpg.de

N. W. Goldberg, X. Shen, J. Li, T. Ritter, Org. Lett., 2016, 18, 6102-6104.

DOI: 10.1021/acs.orglett.6b03086 (free Supporting Information)


Abstract

AlkylFluor, a salt analogue of PhenoFluor, enables a practical, high-yielding deoxyfluorination of various primary and secondary alcohols. AlkylFluor is readily prepared on multigram scale and is stable to long-term storage in air and exposure to water.

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Key Words

fluoroalkanes, benzyl fluorides


ID: J54-Y2016