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Synthesis of Functionalized Indenones via Rh-Catalyzed C-H Activation Cascade Reaction

Ningning Lv, Zhengkai Chen, Yue Liu, Zhanxiang Liu and Yuhong Zhang*

*Department of Chemistry, Zhejiang University, Hangzhou 310027, China, Email:

N. Lv, Z. Chen, Y. Liu, Z. Liu, Y. Zhang, Org. Lett., 2017, 19, 2588-2591.

DOI: 10.1021/acs.orglett.7b00906 (free Supporting Information)

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An efficient rhodium-catalyzed C-H activation and multistep cascade reaction of benzimidates and alkenes enables the synthesis of diverse difunctionalized indenones in the presence of Mn(OAc)2. The transformation involves the cleavage and formation of multiple bonds in one pot under mild reaction conditions.

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Key Words

indenones, Mn(OAc)2

ID: J54-Y2017