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Highly Enantioselective Hydrosilylation of Aromatic Alkenes

Jakob F. Jensen, Bo Y. Svendsen, Thomas V. la Cour, Henriette L. Pedersen and Mogens Johannsen*

*Department of Chemistry, Technical University of Denmark, Building 201, DK-2800 Kgs Lyngby, Denmark, Email: mjkemi.dtu.dk

J. F. Jensen, B. Y. Svendsen, T. V. la Cour, H. L. Pedersen, M. Johannsen, J. Am. Chem. Soc., 2002, 124, 4558-4559.

DOI: 10.1021/ja025617q (free Supporting Information)


Abstract

A novel catalytic system for the asymmetric hydrosilylation of aromatic alkenes is described, which leads to silanes in high yields and with excellent enantioselectivity. The reaction works efficiently for a variety of substituted aromatic alkenes, giving access after Tamao oxidation to almost optically pure benzylic alcohols in high yields.

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Key Words

Benzylsilanes, Tamao Oxidation


ID: J48-Y2002-1100