Copper-Catalyzed Halogen Exchange in Aryl Halides: An Aromatic Finkelstein Reaction
Artis Klapars and Stephen L. Buchwald*
*Department of Chemistry, Massachusetts Institute of Technology, Cambridge,
Massachusetts 02139,
Email: sbuchwal
mit.edu
A. Klapars, S. L. Buchwald, J. Am. Chem. Soc., 2002, 124, 14844-14845.
DOI: 10.1021/ja028865v (free Supporting Information)
Abstract
A mild and general copper(I)-catalyzed conversion of aryl, heteroaryl, and vinyl bromides into the corresponding iodides was developed. Various functional groups and even N-H containing substrates such as sulfonamides, amides, and indoles are compatible with the reaction conditions.
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Key Words
ID: J48-Y2002-1380
