Desymmetrization of Meso 1,3- and 1,4-Diols with a Dinuclear Zinc Asymmetric Catalyst
Barry M. Trost* and Takashi Mino
*Department of Chemistry, Stanford University, Stanford, California
94305-5080, Email: bmtrost
stanford.edu
B. M. Trost, T. Mino, J. Am. Chem. Soc., 2003, 125, 2410-2411.
DOI: 10.1021/ja029708z
Abstract
A dinuclear asymmetric zinc catalyst has been applied for the desymmetrization of some meso diols. The best acyl transfer agent proved to be vinyl benzoate. Diacylation normally did not occur. A model to rationalize the results is presented.
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Key Words
Transesterifications, Desymmetrization of Diols
ID: J48-Y2003-1330
