Flavin Catalyzed Oxidations of Sulfides and Amines with Molecular Oxygen
Yasushi Imada, Hiroki Iida, Satoshi Ono, and Shun-Ichi Murahashi*
*Department of Chemistry, Graduate School of Engineering Science, Osaka
University, 1-3, Machikaneyama, Toyonaka, Osaka 560-8531, Japan, Email: mura
chem.es.osaka-u.ac.jp
Y. Imada, H. Iida, S. Ono, S.-I. Murahashi, J. Am. Chem. Soc., 2003, 125, 2868-2869.
DOI: 10.1021/ja028276p (free Supporting Information)
Abstract
Oxidations of organic substrates such as sulfides, secondary amines, N-hydroxylamines, and tertiary amines with molecular oxygen in the presence of 5-ethyl-3-methyllumiflavinium perchlorate catalyst and hydrazine monohydrate in 2,2,2-trifluoroethanol occur highly efficiently to give the corresponding oxidized compounds in excellent yields.
see article for more reactions
Key Words
Oxygen, Sulfoxides, N-Oxides, Nitrones, Organocatalysis
ID: J48-Y2003-1350
