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Microwave mediated facile one-pot synthesis of polyarylpyrroles from but-2-ene- and but-2-yne-1,4-diones

H. Surya Prakash Rao*, S. Jothilingam and Hans W. Scheeren

*Department of Chemistry, Pondicherry University, Pondicherry 605 014, India, Email: hspryahoo.com

H. S. P. Rao, S. Jothilingam, H. W. Scheeren, Tetrahedron, 2004, 60, 1625-1630.

DOI: 10.1016/j.tet.2003.11.087 (free Supporting Information)


Abstract

Several aryl-substituted pyrrole derivates were prepared conveniently in a microwave-assisted one pot-reaction from but-2-ene-1,4-diones and but-2-yne-1,4-diones via Pd/C-catalyzed hydrogenation of the carbon-carbon double bond/triple bond followed by amination-cyclization.

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Key Words

Pyrroles, Paal-Knorr Pyrrole Synthesis, Hydrogenation, Formate, Microwave Synthesis


ID: J72-Y2004-1330