Organic Chemistry Portal



Efficient Epoxidation of Electron-Deficient Olefins with a Cationic Manganese Complex

Andrew Murphy, Geraud Dubois and T. D. P. Stack*

*Department of Chemistry, Stanford University, Stanford, California 94305, Email:

A. Murphy, G. Dubois, T. D. P. Stack, J. Am. Chem. Soc., 2003, 125, 5250-5251.

DOI: 10.1021/ja029962r (free Supporting Information)


The complex [MnII(R,R-mcp)(CF3SO3)2] is a very efficient and practical catalyst for the epoxidation of a wide scope of olefins including terminal, tertiary, cis and trans internal, enones, and methacrylates using peracetic acid as the terminal oxidant.

see article for more examples

Key Words

Epoxidation, Peracetic Acid, Manganese

Manganese(II)/Picolinic Acid Catalyst System for Epoxidation of Olefins

R. A. Moretti, J. Du Bois, T. D. P. Stack, Org. Lett., 2016, 18, 2528-2531.

Ligand and pH Influence on Manganese-Mediated Peracetic Acid Epoxidation of Terminal Olefins

A. J. Murphy, A. Pace, T. D. P. Stack., Org. Lett., 2004, 6, 3119-3122.

DOI: 10.1021/ol048846l

ID: J48-Y2003-1460