An Expeditious One-Pot Synthesis of Thiiranes from α-Halo Ketones in Solvent-Free Conditions Using Microwaves
Lal Dhar S. Yadav*, Ritu Kapoor
*Department of Chemistry, University of Allahabad, Allahabad 211 002, India,
Email: lds-yadav
hclinfinet.com
L. D. S. Yadav, R. Kapoor, Synthesis, 2002, 2344-2346.
DOI: 10.1055/s-2002-35222
Abstract
Thiiranes are obtained in excellent yields and with high diastereoselectivity upon microwave irradiation of a mixture of α-haloketones, O,O-diethyl hydrogen phosphorodithioate and alumina-supported sodium borohydride in solvent-free conditions.
see article for more examples
Key Words
α-haloketones, thiiranes, stereoselective synthesis, microwave synthesis, solvent free, alumina supported
ID: J66-Y2002-1660
