A Convenient Synthesis of N-Acylpyrroles from Primary Aromatic Amides
Anil R. Ekkati, Dallas K. Bates*
*Department of Chemistry, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA, Email: dbatesmtu.edu
A. R. Ekkati, D. K. Bates, Synthesis, 2003, 1959-1961.
The synthesis of N-acylpyrroles from primary aromatic amides and excess 2,5-dimethoxytetrahydrofuran in presence of one equivalent of thionyl chloride offers short reaction times, mild reaction conditions, and easy workup.
see article for more examples
pyrroles, N-acylpyrroles, primary amides, condensation, 2,5-dimethoxytertahydrofuran