A Convenient Synthesis of N-Acylpyrroles from Primary Aromatic Amides

Anil R. Ekkati, Dallas K. Bates*

*Department of Chemistry, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA, Email: dbatesmtu.edu

A. R. Ekkati, D. K. Bates, Synthesis, 2003, 1959-1961.

DOI: 10.1055/s-2003-41020

---

Abstract

The synthesis of N-acylpyrroles from primary aromatic amides and excess 2,5-dimethoxytetrahydrofuran in presence of one equivalent of thionyl chloride offers short reaction times, mild reaction conditions, and easy workup.

see article for more examples

---

---

Key Words

pyrroles, N-acylpyrroles, primary amides, condensation, 2,5-dimethoxytertahydrofuran

---

ID: J66-Y2003-1960