Indium(III) Chloride/Silica Gel-Promoted Facile and Rapid Cyclization of 2-Aminochalcones to 2-Aryl-2,3-dihydroquinolin-4(1H)-ones under Solvent-Free Conditions

K. Hemanth Kumar, D. Muralidharan, P. T. Perumal*

*Organic Chemistry Division, Central Leather Research Institute, Adyar, Chennai-600 020, India, Email: ptperumalhotmail.com

K. H. Kumar, D. Muralidharan, P. T. Perumal, Synthesis, 2004, 63-68.

DOI: 10.1055/s-2003-44366

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Abstract

A convenient environmentally friendly method for the cyclization of 2-aminochalcones to 2-aryl-2,3-dihydroquinolin-4(1H)-ones on the surface of silica gel impregnated with indium(III) chloride under microwave irradiation without any solvent has been reported.

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Key Words

N-heterocycles, microwave synthesis, indium(III) chloride/silica gel, 2-aminochalcones, solvent-free conditions

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ID: J66-Y2004-1860